Clinical Trials


At KaRa MINDS, we collaborate with international, national and local partners to prevent and treat neurological conditions such as Alzheimer's disease through research.

Current Studies

ANAVEX Study - Recruitment open

A Phase 2b/3, Double-Blind, Randomized, Placebo-Controlled 48-week Safety and Efficacy trial of ANAVEX2-73 for the Treatment of Early Alzheimer’s disease. 

ANAVEX Alzheimer's disease Study – Recruitment open

A Phase 2, Double-blind, randomised, placebo-controlled study to evaluate the safety, tolerability and efficacy of ANAVEX2-73 for cognitive impairment in patients with Parkinson’s Disease with dementia.

Mission AD - Recruitment closed

A Placebo-Controlled, Double-Blind, Parallel-Group, 24-Month Study to Evaluate the Efficacy and Safety of E2609 in Subjects with Early Alzheimer’s Disease.

INmune Bio Study - Recruitment open

An open label 12-week study to investigate the efficacy and safety of XPRO 1595 in Subjects with early-mod Alzheimer's disease.

TotAL Study - Recruitment via Macquarie University (Cognitively Healthy Males)

A 56 week, Double-Blind, Randomised Study to Evaluate the Efficacy of Testosterone, With and Without DHA Supplementation on Cerebral Amyloid Load in Known Brain Amyloid-PET Positive Men with Subjective Memory Complaints.

KARVIAH_XTND Study - Pending

Longitudinal investigational study examining blood, brain and lifestyle risk factors in an older at risk of AD population.

Retinal Study - Access dependent on participation in other studies

Investigating the diagnostic utility of hyperspectral retinal imaging in preclinical Alzheimer’s disease


Previous Studies


Investigation of curcumin for the prevention of Alzheimer’s disease in cognitively healthy individuals, examining the blood, brain and retina.

XanADu Study 

A Phase II, Double -Blind, 12-Week, Randomised, Placebo-Controlled Study to Assess the Safety, Tolerability and Efficacy of XanamemTM  in Subjects with Mild Dementia due to Alzheimer’s disease.


Biomarker qualification for risk of mild cognitive impairment due to Alzheimer’s disease and safety and efficacy evaluation of Pioglitazone in delaying its onset (TOMORROW)


A Phase 2b/3 randomised, double-blind, placebo-controlled, parallel Group, Multicenter Study Investigating the Efficacy and Safety of JNJ-54861911 in subjects who are Asymptomatic and at risk for developing Alzheimer's disease.


A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Aducanumab (BIIB037) in Subjects with early Alzheimer’s disease


A multinational, multi-center, randomized, double-blind, active comparator, phase III clinical trial to evaluate the efficacy and safety of donepezil transdermal patch in patients with Alzheimer’s disease.


For further details on any study, please call KaRa MINDS or use the Contact Us form at the bottom of the page and our friendly team will be in touch.